BINDING OF THIOSTREPTON TO A COMPLEX OF 23-S RIBOSOMAL-RNA WITH RIBOSOMAL PROTEIN-L11

被引：86

作者：

THOMPSON, J

CUNDLIFFE, E

STARK, M

机构：

[1] Department of Biochemistry, University of Leicester, Leicester, LE1 7HR, University Road

来源：

EUROPEAN JOURNAL OF BIOCHEMISTRY | 1979年 / 98卷 / 01期

关键词：

D O I：

10.1111/j.1432-1033.1979.tb13184.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Thiostrepton binds with high affinity and with a 1:1 stoichiometry to a complex formed between Escherichia coli 23‐S ribosomal RNA and ribosomal protein L11 of E. coli or the homologous protein BM‐L11 of Bacillus megaterium. In the presence of T1 ribonuclease, protein BM‐L11 and thiostrepton protect from degradation a fragment of E. coli 23‐S RNA estimated to be about 50 nucleotides in length. Copyright © 1979, Wiley Blackwell. All rights reserved

引用

页码：261 / 265

页数：5

共 12 条

[1]

COOPERMAN BS, 1978, BIOORG CHEM, V4, P81

[2]

CUNDLIFFE E, 1979, J MOL BIOL, V131

[3]

CUNDLIFFE E, 1979, ANTIBIOTICS, V5

[4] PROPERTIES OF RIBOSOMES OF ANTIBIOTIC PRODUCERS - EFFECTS OF THIOSTREPTON AND MICROCOCCIN ON ORGANISMS WHICH PRODUCE THEM [J].