MOUSE LEUKEMIA VIRUS ACTIVATION BY CHEMICAL CARCINOGENS

被引：106

作者：

IGEL, HJ

HUEBNER, RJ

TURNER, HC

KOTIN, P

FALK, HL

机构：

[1] Children's Hospital, Akron

[2] National Cancer Institute, Bethesda

[3] National Institute of Environmental Health Sciences, Research Triangle Park, NC

来源：

SCIENCE | 1969年 / 166卷 / 3913期

关键词：

D O I：

10.1126/science.166.3913.1624

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The induction of lymphomas in C57BL mice by methylcholanthrene, urethan, or diethylnitrosamine was accompanied by the development of murine leukemia viral antigen in most of the lymphoid tumors. The cell-free transmission of lymphomas induced by methylcholanthrene and the development of antibody to murine leukemia virus prior to the detection of overt lymphoma in these mice suggest that unmasking of a latent leuikemia viruis is an indigenous actuating cause of the lymphomas.

引用

页码：1624 / &

共 17 条

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[2] MECHANISM OF RADIATION ACTION IN LEUKAEMOGENESIS - ISOLATION OF A LEUKAEMOGENIC FILTRABLE AGENT FROM TISSUES OF IRRADIATED AND NORMAL C57BL MICE
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HUEBNER, RJ
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[6] ISOLATION OF NATURALLY OCCURRING VIRUSES OF MURINE LEUKEMIA VIRUS GROUP IN TISSUE CULTURE
HARTLEY, JW
ROWE, WP
CAPPS, WI
HUEBNER, RJ
[J]. JOURNAL OF VIROLOGY, 1969, 3 (02) : 126 - &
[7] HARTLEY JW, 1967, P NATL ACAD SCI USA, V58, P835
[8] RESCUE OF DEFECTIVE MURINE SARCOMA VIRUS GENOME BY RADIATION-INDUCED LEUKEMIA VIRUS FROM C57BL MICE
IGEL, H
HUEBNER, RJ
DEPPA, B
BUMGARNER, S
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1967, 58 (05) : 1870 - +
[9] IRINO S, 1963, GANN, V54, P225
[10] IRINO S, 1968, GANN, V59, P223

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