CHROMOSOME-ABERRATIONS IN PSORIATIC PATIENTS TREATED WITH ARSENIC

被引:46
作者
NORDENSON, I [1 ]
SALMONSSON, S [1 ]
BRUN, E [1 ]
BECKMAN, G [1 ]
机构
[1] UMEA UNIV,DEPT MED GENET,S-90185 UMEA,SWEDEN
关键词
D O I
10.1007/BF00273266
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
A significantly increased frequency of chromosomal aberrations was found in lymphocytes from eight psoriatic patients previously treated with arsenic than in lymphocytes from eight psoriatics with no such previous treatment. In most patients the arsenic therapy was discontinued more than 15 years ago. In the arsenic-treated group a statistically significant heterogeneity was found with respect to the frequency of aberrations. The frequency of sister chromatid exchange was not increased in the arsenic-treated patients. © 1979 Springer-Verlag.
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页码:1 / 6
页数:6
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