SYNTHESIS OF THE NOVEL ANTILEUKEMIC TETRAHYDROCYCLOPENTA[B]BENZOFURAN, ROCAGLAMIDE

被引：23

作者：

DAVEY, AE ^{[1
]}

SCHAEFFER, MJ ^{[1
]}

TAYLOR, RJK ^{[1
]}

机构：

[1] UNIV E ANGLIA,SCH CHEM SCI,NORWICH NR4 7TJ,NORFOLK,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1991年 / 16期

关键词：

D O I：

10.1039/c39910001137

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A total synthesis of the novel anti-leukaemic natural product, rocaglamide, in racemic form, is described, the key step involving an intramolecular keto-aldehyde pinacolic coupling; the synthetic route is short, proceeds from phloroglucinol, a readily-available starting material, and is well suited to the synthesis of analogues.

引用

页码：1137 / 1139

页数：3

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