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LIPOPROTEIN TRANSPORT GENE ABNORMALITIES UNDERLYING CORONARY HEART-DISEASE SUSCEPTIBILITY

被引：24
作者：
BRESLOW, JL
机构：
[1] Lab. of Biochem. Genet. and Metab., Rockefeller University, New York
来源：
ANNUAL REVIEW OF MEDICINE | 1991年 / 42卷
关键词：
GENETICS; ATHEROSCLEROSIS; APOLIPOPROTEINS;
D O I：
10.1146/annurev.me.42.020191.002041
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
There is a close association between lipoprotein abnormalities and coronary heart disease susceptibility. Since 1982, the genes for the lipoprotein transport proteins have been isolated and at least partially characterized. Mutations in these genes are now being defined that underlie the common abnormalities found in heart attack victims. This review presents our current state of knowledge on this subject.
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页码：357 / 371
页数：15
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