PULMONARY INTERSTITIAL CHANGES FOLLOWING BONE-MARROW TRANSPLANTATION - COMPLEX, MULTIFACTOR DISORDER

被引：30

作者：

KHOURI, NF

SARAL, R

ARMSTRONG, EM

TUTSCHKA, PJ

SANTOS, GW

BESCHORNER, WE

SIEGELMAN, SS

机构：

[1] JOHNS HOPKINS MED INST,DEPT RADIOL,BALTIMORE,MD 21205

[2] JOHNS HOPKINS MED INST,DEPT MED,BALTIMORE,MD 21205

[3] JOHNS HOPKINS MED INST,DEPT ONCOL,BALTIMORE,MD 21205

[4] JOHNS HOPKINS MED INST,DEPT PATHOL,BALTIMORE,MD 21205

来源：

RADIOLOGY | 1979年 / 133卷 / 03期

关键词：

D O I：

10.1148/133.3.587

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Observations of 20 consecutive bone marrow transplantation recipients disclosed two distinctive categories of pulmonary interstitial changes. Interstitial infiltrates occurring less than 14 days after transplantation were observed in 13 of 20 patients and are believed to represent pulmonary edema. A late pulmonary interstitial process, which appears more than 30 days following transplantation (median 57 days), was encountered in 10 of 14 patients with successful grafts; the late changes represent interstitial pneumonia, a common cause of morbidity and mortality following bone marrow transplantation. It is probably attributable to a combination of factors including the preparatory chemotherapy and radiotherapy, and delayed immunologic reconstitution following transplantation.

引用

页码：587 / 592

页数：6

共 21 条

[1] LYMPHOCYTIC BRONCHITIS ASSOCIATED WITH GRAFT VERSUS HOST DISEASE IN RECIPIENTS OF BONE-MARROW TRANSPLANTS [J].