SYNTHESIS OF AMINO-ACID DERIVATIVES OF NEAMINE AND 2-DEOXYSTREPTAMINE TO BE USED AS MUTASYNTHONS

被引:19
作者
GEORGIADIS, MP [1 ]
CONSTANTINOUKOKOTOU, V [1 ]
KOKOTOS, G [1 ]
机构
[1] UNIV ATHENS,DEPT CHEM,ATHENS,GREECE
关键词
D O I
10.1080/07328309108543947
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
6'-N derivatives of neamine with alanine, phenylalanine and lysine were synthesized either using an active esters method in one step under controlled conditions, or using a mixed anhydride method after blocking every functional group of neamine and leaving the 6'-amino group free to react. Similarly N,N'-diamino acid and monoamino acid derivatives of 2-deoxystreptamine were synthesized.
引用
收藏
页码:739 / 748
页数:10
相关论文
共 19 条