AMARIIN, A DI-DEHYDROHEXAHYDROXYDIPHENOYL HYDROLYZABLE TANNIN FROM PHYLLANTHUS-AMARUS

Amariin, a novel hydrolysable tannin together with geraniin. corilagin. 1,6-digalloylglucopyranoside as well as rutin and quercetin-3-0-glucopyranoside were isolated from the polar fraction of Phyllanthus amarus. On the basis of spectroscopic data and inverse long range H-1, C-13 correlation experiments on its phenazine derivative, the structure of amariin was established as 1-galloyl-2,4:3,6-bis-DHHDP-glucopyranoside in which the cyclohexenetrione portion of the DHHDP moieties were linked to the 0-3 and 0-4 of the glucose moiety.