NEUROPATHOLOGICAL CHANGES IN THE CAUDATE-NUCLEUS ELICITED BY MPTP AND THEIR PREVENTION BY MONOAMINE-OXIDASE INHIBITION

被引：8

作者：

HESS, A

机构：

来源：

BRAIN RESEARCH | 1989年 / 499卷 / 02期

关键词：

D O I：

10.1016/0006-8993(89)90791-9

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

引用

页码：393 / 396

页数：4

共 10 条

[1] A PRIMATE MODEL OF PARKINSONISM - SELECTIVE DESTRUCTION OF DOPAMINERGIC-NEURONS IN THE PARS COMPACTA OF THE SUBSTANTIA NIGRA BY N-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE [J].

BURNS, RS ;

CHIUEH, CC ;

MARKEY, SP ;

EBERT, MH ;

JACOBOWITZ, DM ;

KOPIN, IJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (14) :4546-4550

[2] DOPAMINERGIC NEUROTOXICITY OF 1-METHYL-4-PHENYL-1,2,5,6-TETRAHYDROPYRIDINE (MPTP) IN THE MOUSE - RELATIONSHIPS BETWEEN MONOAMINE-OXIDASE, MPTP METABOLISM AND NEUROTOXICITY [J].

HEIKKILA, RE ;

HESS, A ;

DUVOISIN, RC .

LIFE SCIENCES, 1985, 36 (03) :231-236

[3] DOPAMINERGIC NEUROTOXICITY OF 1-METHYL-4-PHENYL-1,2,5,6-TETRAHYDROPYRIDINE IN MICE [J].

HEIKKILA, RE ;

HESS, A ;

DUVOISIN, RC .

SCIENCE, 1984, 224 (4656) :1451-1453

[4]

HEIKKILA RE, 1984, NATURE, V311, P467, DOI 10.1038/311467a0

[5]

Hess A., UNPUB

[6] CHRONIC PARKINSONISM IN HUMANS DUE TO A PRODUCT OF MEPERIDINE-ANALOG SYNTHESIS [J].

LANGSTON, JW ;

BALLARD, P ;

TETRUD, JW ;

IRWIN, I .

SCIENCE, 1983, 219 (4587) :979-980

[7] INTRANEURONAL GENERATION OF A PYRIDINIUM METABOLITE MAY CAUSE DRUG-INDUCED PARKINSONISM [J].

MARKEY, SP ;

JOHANNESSEN, JN ;

CHIUEH, CC ;

BURNS, RS ;

HERKENHAM, MA .

NATURE, 1984, 311 (5985) :464-467

[8] INHIBITION OF NADH-LINKED OXIDATION IN BRAIN MITOCHONDRIA BY 1-METHYL-4-PHENYL-PYRIDINE, A METABOLITE OF THE NEUROTOXIN, 1-METHYL-4-PHENYL-1,2,5,6-TETRAHYDROPYRIDINE [J].

NICKLAS, WJ ;

VYAS, I ;

HEIKKILA, RE .

LIFE SCIENCES, 1985, 36 (26) :2503-2508

[9] ACUTE ADMINISTRATION OF 1-N-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP), A COMPOUND PRODUCING PARKINSONISM IN HUMANS, STIMULATES [2-C-14]-LABELED DEOXYGLUCOSE UPTAKE IN THE REGIONS OF THE CATECHOLAMINERGIC CELL-BODIES IN THE RAT AND GUINEA-PIG BRAINS [J].

PALACIOS, JM ;

WIEDERHOLD, KH .

BRAIN RESEARCH, 1984, 301 (01) :187-191

[10] ADMINISTRATION OF MPTP ACUTELY INCREASES GLUCOSE-UTILIZATION IN THE SUBSTANTIA NIGRA OF PRIMATES [J].

PALOMBO, E ;

PORRINO, LJ ;

BANKIEWICZ, KS ;

CRANE, AM ;

KOPIN, IJ ;

SOKOLOFF, L .

BRAIN RESEARCH, 1988, 453 (1-2) :227-234

← 1 →