THE USEFULNESS OF ENDOMETRIAL BIOPSY FOR LUTEAL PHASE EVALUATION IN INFERTILITY

被引：54

作者：

BALASCH, J

FABREGUES, F

CREUS, M

VANRELL, JA

机构：

[1] Department of Obstetrics and Gynaecology, Faculty of Medicine, Hospital Clinic i Provincial

来源：

HUMAN REPRODUCTION | 1992年 / 7卷 / 07期

关键词：

LUTEAL PHASE DEFICIENCY; ENDOMETRIAL BIOPSY; INFERTILITY;

D O I：

10.1093/oxfordjournals.humrep.a137782

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

To assess the usefulness of the late luteal phase endometrial biopsy in infertility, we evaluated a total of 1492 biopsies performed in 1055 patients. Of these women, 699 underwent one biopsy during spontaneous ovulatory cycles, 288 had two, 57 had three, nine had four, and rive biopsies were done in two patients. As controls we included 45 fertile women who were requesting contraception. We analysed histological dating of the endometrium and its abnormality rates in first and successive biopsy specimens, as well as the association of the pregnancy outcome with the endometrial patterns and treatment for luteal phase deficiency (LPD). Our results show firstly that diagnosis of LPD in both infertile and fertile women represents only a chance event; secondly, histological endometrial adequacy or inadequacy in the cycle of conception or in previous cycles is not related to the outcome of pregnancy in infertile patients. Finally, treatment of LPD does not improve pregnancy outcome in infertile women. Thus, luteal phase evaluation by histological dating of the endometrium is not worthwhile.

引用

页码：973 / 977

页数：5

共 26 条

[1] Balasch J., Vanrell J.A., Corpus luteum insufficiency and fertility: A matter of controversy, Hum. Reprod, 2, pp. 557-567, (1987)
[2] Balasch J., Vanrell J.A., Mdrquez M., Burzaco I., Gonzilez-Merlo J., Dehydrogesterone versus vaginal progesterone in the treatment of the endometrial luteal phase deficiency, Fertil. Steril, 37, pp. 751-754, (1982)
[3] Balasch J., Vanrell J.A., Mdrquez M., Gonzijez-Merlo J., Dehydrogesterone treatment of endometrial luteal phase deficiency after ovulation induced by clomiphene citrate and human chorionic gonadotropin, Fertil. Steril, 40, pp. 469-471, (1983)
[4] Balasch J., Vanrell J.A., Mdrquez M., Gonzilez-Merlo J., Endometrial biopsy inadvertently taken in the cycle of conception, Int. J. Gynaecol. Obstet, 22, pp. 95-99, (1984)
[5] Balasch J., Vanrell J.A., Creus M., Mfirquez M., Gonzalez-Merlo J., The endometrial biopsy for diagnosis of luteal phase deficiency, Fertil. Steril, 44, pp. 699-701, (1985)
[6] Balasch J., Creus M., Mdrquez M., Burzaco I., Vanrell J.A., The significance of luteal phase deficiency on fertility: A diagnostic and therapeutic approach, Hum. Reprod, 1, pp. 145-147, (1986)
[7] Daly Walters D.C.C.A., Soto-Albors C.E., Riddick D.H., Endometrial biopsy during treatment of luteal phase defects is predictive of therapeutic outcome, Fertil. Steril, 40, pp. 305-310, (1983)
[8] Davidson B.J., Thrasher T.V., Seraj L.M., An analysis of endometnal biopsies performed for infertility, Fertil. Steril, 48, pp. 770-774, (1987)
[9] Di Paola G.R., Mandez Ribas J.M., Arrighi L.A., Critical study of the retarded progestational phase, Int. J. Fertil, 16, pp. 189-194, (1971)
[10] Driessen F., Holwerda P.J., Putte S.C., Kremer J., The significance of dating an endometrial biopsy for the prognosis of the infertile couple, Int. J. Fertil, 25, pp. 112-116, (1980)

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