EXPERIENCE WITH LIVING-RELATED DONOR NEPHRECTOMY - EVALUATION OF 200 CASES

被引:6
作者
ABOMELHA, MS
ASSARI, S
SHAABAN, A
ALOTAIBI, K
KOURAH, M
机构
[1] Department of Urology, Riyadh Armed Forces Hospital, Riyadh 11159
关键词
D O I
10.5144/0256-4947.1993.416
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Over a ten year period (1979 to 1989), 200 patients have undergone live donor nephrectomy through a flank extraperitoneal approach without rib resection. The average hospital stay was short and the major complications were negligible. Early graft function was seen in 97% of the cases. Delayed function due to acute tubular necrosis developed in 3%. Urinary leak was seen in 3%. Two kidneys were lost due to infection related to urinary fistulae. In 70 donors, 37 +/- 23 months' follow-up was available. Hypertension developed in two patients three and three and one-half years post donation. Significant proteinuria (>300 mg/day) was noted in one patient. No significant renal functional abnormalities were observed. Creatinine clearance was about 70% of the initial measurement at the observation time. We conclude that extraperitoneal flank live donor nephrectomy is generally safe and associated with minimal perioperative and long-term morbidity. Moreover, the procedure provides an excellent allograft function.
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收藏
页码:416 / 419
页数:4
相关论文
共 20 条
[1]  
Sutherland DER, Living-related donors should be used whenever possible., Transplant Proc, 17, (1985)
[2]  
Spital A, The living kidney donor: alive and well., Arch Intern Med, 146, (1986)
[3]  
Shimamura T, A progressive glomerulosclerosis occurring in partial five-sixths nephrectomy., Am J Path, 79, (1975)
[4]  
Dworkin LD, Hemodynamic basis for glomerular injury in rats with desoxycorticosterone-salt hypertension., J Clin Invest, 73, (1984)
[5]  
Brenner BM, Nephron adaptation to renal injury or ablation., Am J Physiol, 249, (1985)
[6]  
Vicenti F, Long-term renal function in kidney donors: sustained compensatory hyperfiltration with no adverse effects., Transplantation, 36, (1983)
[7]  
Hakim RM, Hypertension and proteinuria: long-term sequelae of uninephrectomy in humans., Kidney Int, 25, (1984)
[8]  
Miller IJ, Impact of renal donation: long-term clinical and biochemical follow-up of living donors in a single center., Am J Med, 79, (1985)
[9]  
Anderson CV, The risks of unilateral nephrectomy: status of kidney donors ten to twenty years postoperatively., Mayo Clin Proc, 60, (1985)
[10]  
Talseth T, Long-term blood pressure and renal function in kidney donors., Kidney Int, 29, (1986)