DISTRIBUTION OF O-6-METHYLGUANINE IN RAT DNA FOLLOWING PRETREATMENT INVIVO WITH METHYLNITROSOUREA

被引：12

作者：

CHANG, MJW ^{[1
]}

WEBB, TE ^{[1
]}

KOESTNER, A ^{[1
]}

机构：

[1] OHIO STATE UNIV,DEPT PHYSIOL CHEM,COLUMBUS,OH 43210

来源：

CANCER LETTERS | 1979年 / 6卷 / 03期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0304-3835(79)80022-1

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Methylation of guanine at its O6 position occurred in both the unique and the repetitive DNA sequences in several rat organs following an in vivo pretreatment with the carcinogen N-methyl-N-nitrosourea. Little or no difference was found in the distribution of O6-methylguanine between the 2 DNA fractions. © 1979 Elsevier/North-Holland Scientific Publishers Ltd., All rights reserved.

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页码：123 / 127

页数：5

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