COMPARISON OF TC-99M AEROSOL AND KRYPTON-81M IN VENTILATION STUDIES FOR THE DIAGNOSIS OF PULMONARY-EMBOLISM

被引：33

作者：

PELTIER, P

DEFAUCAL, P

CHETANNEAU, A

CHATAL, JF

机构：

[1] Centre Réné Gauducheau, Service de Médecine Nucléaire, Nantes, 44035, Quai Moncousu

来源：

NUCLEAR MEDICINE COMMUNICATIONS | 1990年 / 11卷 / 09期

关键词：

D O I：

10.1097/00006231-199009000-00006

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

A new method of producing aerosols (technegas) in which99Tcmis bound to carbon atoms (99Tcm-C) was evaluated by comparing99Tcm-C images with those obtained with81Krmin the same patients. Twenty-five patients with suspected pulmonary embolism (PE) were studied. Immediately after the last99Tcm-C view, the patients remained in supine position and inhaled81Krmat tidal volume. Immediately after the81Krmventilation views were recorded, 4-7 mCi of MAA were injected IV. The same four views (ant, lop, rop, post) were recorded after inhalation of99Tcm-C and 81Krm (200 kcounts) and99TcmMAA injection (400 kcounts). The mean penetration index of99Tcm-C (0.91) was lower than that of81Krm(1.04) (P<0.03). The apex to base lung distribution of99Tcm-C and81Krmappeared to be similar. The mean heterogeneity of 99Tcm distribution was 23, greater than that of81Krm(14) (P = 10-4). The99Tcm-C ventilation image quality was considered very good for 16 patients and good for 6 others. Significant foci of high bronchial uptake were infrequent. Interpretation of the examinations performed after inhalation of99Tcm-C and81Krmwas concordant in all cases. No patient had an81Krm/99TcmMAA examination suggestive of PE when99Tcm-C/99TcmMAA indicated a low probability of PE, and vice versa.99Tcm-C aerosols enable good quality ventilation images to be obtained in nearly all cases. Thus99Tcm-C aerosols could be used in preference to81Krmin ventilation studies for the diagnosis of PE. © 1990 Chapman and Hall Ltd.

引用

页码：631 / 638

页数：8

共 15 条

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