ASYMMETRIC HYDROGENATION OF METHYL PYRUVATE USING PT-C CATALYST MODIFIED WITH CINCHONIDINE

被引：106

作者：

ORITO, Y

IMAI, S

NIWA, S

机构：

[1] National Chemical Laboratory for Industry, Honmacki, Shibuya-ku

来源：

NIPPON KAGAKU KAISHI | 1979年 / 08期

关键词：

D O I：

10.1246/nikkashi.1979.1118

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The asymmetric hydrogenation of methyl pyruvate to (+)-methyl lactate using Pt-C catalyst modified with cinchonidine was studied. Preheating of the catalyst at 200~400°C in hydrogen atmosphere before modification with cinchonidine was found to be necessary for high asymmetric-inducing activity to be acquired. The catalyst thus prepared had high asymmetric selectivity (optical yield=78.7%) in ethanol containing a small amount of cinchonidine. © 1979, The Chemical Society of Japan. All rights reserved.

引用

页码：1118 / 1120

页数：3