POSTOPERATIVE RADIOTHERAPY AFTER PNEUMONECTOMY - IMPACT OF MODERN TREATMENT FACILITIES

被引:48
作者
PHILIPS, P
ROCMANS, P
VANDERHOEFT, P
VANHOUTTE, P
机构
[1] INST JULES BORDET, DEPT RADIAT ONCOL, RUE HEGER BORDET 1, B-1000 BRUSSELS, BELGIUM
[2] HOP ERASME, DEPT THORAC SURG, BRUSSELS, BELGIUM
来源
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS | 1993年 / 27卷 / 03期
关键词
LUNG CANCER; POSTOPERATIVE RADIOTHERAPY; CT SCAN;
D O I
10.1016/0360-3016(93)90375-6
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Purpose: The present study was undertaken to see how modern treatment facilities, computed tomography (CT)-based treatment planning and linear accelerator, have modified the results of postoperative irradiation after a pneumonectomy for lung cancer. Methods and Materials: Between 1970-1985, 103 patients were treated in our department after a pneumonectomy: 50 patients with a T1T2N0 tumor and 53 patients with a T3, N1 or N2 tumor. Three groups were considered: 27 patients had only surgical resection, 51 patients were irradiated postoperatively with a Co60 source, and 25 patients were treated using those modern facilities. Results: The 5-year survival varies from 4% to 31% according to the tumor extent but also to the radiation technique. Patients treated with a Co60 source had a dismal 5-year survival rate (8%) whereas patients treated with the modern facilities had a 5-year survival rate of 30% similar to the 31% of the control surgical group including less advanced tumors. Conclusion: Linear accelerator and computed tomography-based treatment planning improved the accuracy of postoperative thoracic irradiation and allow to deliver high doses to the mediastinum even after a pneumonectomy.
引用
收藏
页码:525 / 529
页数:5
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