A MILD METHOD FOR THE ALCOHOLYSIS OF BETA-LACTAMS

被引：32

作者：

PALOMO, C

AIZPURUA, JM

CUEVAS, C

MIELGO, A

GALARZA, R

机构：

[1] Departamento de Química Orgánica. Facultad, Química. Universidad del Pais Vasco, 20080 San Sebastián

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 49期

关键词：

D O I：

10.1016/0040-4039(95)01903-U

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Ring opening reaction of N-Boc-azetidinones using alcohols is greatly enhanced by NaN3 or KCN. Extremely mild and neutral reaction conditions are described favouring the reaction with hindered alcohols and precluding epimerization of enolizable substrates.

引用

收藏

页码：9027 / 9030

页数：4

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