AN IMPROVED CATION-EXCHANGE HPLC METHOD FOR THE MEASUREMENT OF SERUM CREATININE

被引:13
作者
GUY, JM
LEGG, EF
机构
[1] Department of Clinical, Chemistry, East Birmingham Hospital, Birmingham B9 5ST, Bordesley Green East
关键词
HPLC compared to Jaffe method; single buffer ion exchange; specific determination of creatinine;
D O I
10.1177/000456329002700307
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
An improved HPLC method for the measurement of serum creatinine is described. Separation is effected using a strong cation exchange column at pH 4.7. Analytical recovery, precision and linearity are satisfactory, and the method correlates well with a kinetic Jaffe procedure. The method provides a means of accurately measuring creatinine and may be of use in the investigation of interference in creatinine assays.
引用
收藏
页码:223 / 226
页数:4
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