BIOLOGICAL CHEMISTRY OF ALUMINUM STUDIED USING AL-26 AND ACCELERATOR MASS-SPECTROMETRY

被引：28

作者：

DAY, JP

BARKER, J

KING, SJ

MILLER, RV

TEMPLAR, J

LILLEY, JS

DRUMM, PV

NEWTON, GWA

FIFIELD, LK

STONE, JOH

ALLAN, GL

EDWARDSON, JA

MOORE, PB

FERRIER, IN

PRIEST, ND

NEWTON, D

TALBOT, RJ

BROCK, JH

SANCHEZ, L

DOBSON, CB

ITZHAKI, RF

RADUNOVIC, A

BRADBURY, MWB

机构：

[1] SERC,DARESBURY LAB,NUCL STRUCT FACIL,WARRINGTON WA4 4AD,CHESHIRE,ENGLAND

[2] AUSTRALIAN NATL UNIV,DEPT NUCL PHYS,CANBERRA,ACT 2600,AUSTRALIA

[3] NEWCASTLE GEN HOSP,MRC,NEUROCHEM PATHOL UNIT,NEWCASTLE TYNE NE4 6BE,TYNE & WEAR,ENGLAND

[4] AEA TECHNOL,BIOMED RES DEPT,HARWELL,ENGLAND

[5] UNIV GLASGOW,DEPT IMMUNOL,GLASGOW G12 8QQ,SCOTLAND

[6] UNIV MANCHESTER,INST SCI & TECHNOL,DEPT OPTOMETRY & VIS SCI,MANCHESTER M60 1QD,LANCS,ENGLAND

[7] UNIV LONDON KINGS COLL,DEPT PHYSIOL,LONDON WC2R 2LS,ENGLAND

来源：

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS | 1994年 / 92卷 / 1-4期

基金：

英国惠康基金;

关键词：

D O I：

10.1016/0168-583X(94)96055-0

中图分类号：

TH7 [仪器、仪表];

学科分类号：

0804 ; 080401 ; 081102 ;

摘要：

Developments in sample preparation and presentation for accelerator mass spectrometry now permit the determination of Al-26/Al-27 ratios in biological materials with an accuracy of ca. 2%. We describe the use of Al-26 as a tracer for aluminium, in a number of biological experiments which demonstrate the power of this technique to determine Al content and distribution within complex chemical and biological systems, and to investigate the kinetics and mechanisms of Al-transport pathways. Applications to human, animal and cellular systems are described.

引用

页码：463 / 468

页数：6

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