FAMILIAL AGGREGATION OF LEISHMANIA-CHAGASI INFECTION IN NORTHEASTERN BRAZIL

被引：42

作者：

CABELLO, PH

LIMA, AMVMD

AZEVEDO, ES

KRIEGER, H

机构：

[1] UNIV FED BAHIA,MED GENET LAB,BR-40210 SALVADOR,BA,BRAZIL

[2] UNIV SAO PAULO,DEPT PARASITOL,BR-05508 SAO PAULO,BRAZIL

来源：

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE | 1995年 / 52卷 / 04期

关键词：

D O I：

10.4269/ajtmh.1995.52.364

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

A sample of 1,604 individuals belonging to 243 nuclear families from an endemic area of visceral leishmaniasis (Jacobina, Bahia State, Brazil) was studied to disclose the intrafamilial pattern of infection. Significant father to offspring, mother to offspring, and sibling to sibling associations, in contrast a with nonsignificant father to mother association, clearly indicate a familial aggregation of the infection, with a strong suggestion of at least partial genetic involvement.

引用

页码：364 / 365

页数：2

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