LINEAR GROWTH AFTER COLECTOMY FOR ULCERATIVE-COLITIS IN CHILDHOOD

被引：27

作者：

NICHOLLS, S

VIEIRA, MC

MAJROWSKI, WH

SHAND, WS

SAVAGE, MO

WALKERSMITH, JA

机构：

[1] ST BARTHOLOMEWS HOSP,DEPT PAEDIAT GASTROENTEROL,LONDON EC1A 7BE,ENGLAND

[2] ST BARTHOLOMEWS HOSP,DEPT SURG,LONDON EC1A 7BE,ENGLAND

[3] ST BARTHOLOMEWS HOSP,DIV PAEDIAT ENDOCRINOL,LONDON EC1A 7BE,ENGLAND

来源：

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION | 1995年 / 21卷 / 01期

关键词：

GROWTH; COLITIS; COLECTOMY; CHILDHOOD;

D O I：

10.1097/00005176-199507000-00014

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Eighteen children and adolescents, of a total of 90 treated in our unit between 1982 and 1992, underwent colectomy for ulceractive colitis. Six (6.7%) of the 90 patients had short stature, i.e., a height below the 3rd centile, and 8 of the 18 who had surgery had a subnormal height velocity, i.e., below the 25th centile for age at the time of surgery, Surgery was performed for resistance to medical therapy (n = 13) or toxic megacolon (n = 5). Surgery was followed by catch-up growth, i.e., increasing height velocity, in eight subjects and cessation of the trend of diminishing height velocity, but without catch-up growth, in five, In 11 of the subjects who were prepubertal, the median height velocity increased from 3.85 cm/year preoperatively to 7.35 cm/year postoperatively (p < 0.01). One year after surgery, 14 of the 18 patients were either asymptomatic or substantially improved. Surgery therefore Led to improved linear growth and a prolonged symptom-free period in most of the children and adolescents with ulcerative colitis undergoing this treatment.

引用

页码：82 / 86

页数：5

共 21 条

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