EFFECTS OF AGE, STRAIN, AND DIETARY CARBOHYDRATE ON THE HEPATIC-METABOLISM OF MALE RATS

被引：27

作者：

BERDANIER, CD

TOBIN, RB

DEVORE, V

机构：

[1] UNIV NEBRASKA, COLL MED, DEPT BIOCHEM, OMAHA, NE 68105 USA

[2] UNIV NEBRASKA, COLL MED, DEPT MED, OMAHA, NE 68105 USA

[3] VET ADM HOSP, OMAHA, NE 68105 USA

来源：

JOURNAL OF NUTRITION | 1979年 / 109卷 / 02期

关键词：

D O I：

10.1093/jn/109.2.261

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

The effects of age and the duration of feeding either a 65% sucrose or a 65% starch diet to normolipemic Wistar and potentially hyperlipemic-hyperglycemic BHE male rats on hepatic metabolite levels and calculated redox and phosphorylation states were studied. The feeding of sucrose to BHE rats hastened the appearance of hyperlipemia while having little effect in Wistar rats. The changes in hepatic metabolites were consistent with an increased hepatic lipogenesis in BHE rats. The results suggest that the effects of feeding sucrose to BHE rats potentiate the genetically increased hepatic lipogenesis in these rats.

引用

页码：261 / 271

页数：11

共 35 条

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