DILTIAZEM INHIBITS THE SPONTANEOUS PLATELET-AGGREGATION IN ESSENTIAL-HYPERTENSION

被引：13

作者：

PECHAN, J

OKRUCKA, A

机构：

[1] Department of Internal Medicine, Comenius University, Bratislava

来源：

CARDIOLOGY | 1991年 / 79卷 / 02期

关键词：

DILTIAZEM; PLATELET AGGREGATION; ESSENTIAL HYPERTENSION; BETA-THROMBOGLOBULIN;

D O I：

10.1159/000174868

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Plasma beta-thromboglobulin, initial (spontaneous) and total platelet aggregation, induced by adrenaline or ADP, were determined in 15 patients with essential hypertension before and after 1 week of diltiazem therapy. Diltiazem significantly decreased the spontaneous platelet aggregation in a therapeutic dose of 3 x 60 mg/day. This antiaggregatory effect is the further advantage of the antihypertensive therapy with diltiazem that may be of importance for the inhibition of atherosclerotic and thrombotic complications in essential hypertension.

引用

页码：116 / 119

页数：4

共 17 条

[1] EFFECTS OF VERAPAMIL AND DILTIAZEM ON HUMAN-PLATELET FUNCTION [J].