COMPARISON OF CADMIUM, MERCURY AND CALCIUM ACCUMULATIONS BY ISOLATED HEPATOCYTES OF THE SMALL SKATE (RAJA-ERINACEA) AND RAT

被引：10

作者：

BLAZKA, ME

YOSHIDA, M

SHAIKH, ZA

机构：

[1] UNIV RHODE ISL,DEPT PHARMACOL & TOXICOL,KINGSTON,RI 02881

[2] MT DESERT ISL BIOL LAB,SALSBURY COVE,ME 04672

来源：

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY | 1992年 / 101卷 / 03期

关键词：

D O I：

10.1016/0742-8413(92)90098-R

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. Accumulation of calcium, cadmium and mercury by isolated hepatocytes of the small skate (Raja erinacea) and rat was examined at 14 and 37-degrees-C, respectively. 2. Metal uptakes by both species were biphasic, with rat cells accumulating more metal than the skate cells. 3. Total accumulation after 30 min was in the order: mercury = cadmium much greater than calcium. 4. In both species calcium and cadmium accumulations were reduced at 4-degrees-C, while mercury accumulation was not. 5. Cd accumulation was increased by Cu and Hg in both species. 6. Hg accumulation was inhibited by Cu in both species, and increased by Cd only in the rat cells.

引用

页码：631 / 639

页数：9

共 39 条

[1] ALTERED PLASMA-MEMBRANE ION PERMEABILITY IN MERCURY-INDUCED CELL INJURY - STUDIES IN HEPATOCYTES OF ELASMOBRANCH RAJA-ERINACEA [J].