RAT INTESTINAL EPITHELIAL-CELL LINE IEC-6 IS ACTIVATED BY RECOMBINANT INTERFERON-GAMMA TO INHIBIT REPLICATION OF THE COCCIDIAN TOXOPLASMA-GONDII

被引：24

作者：

DIMIER, IH ^{[1
]}

BOUT, DT ^{[1
]}

机构：

[1] UNIV TOURS,INRA,UFR SCI PHARMACEUT,UNITE RECH,F-37041 TOURS,FRANCE

来源：

EUROPEAN JOURNAL OF IMMUNOLOGY | 1993年 / 23卷 / 04期

关键词：

TOXOPLASMA-GONDII; ENTEROCYTE; INTERFERON-GAMMA;

D O I：

10.1002/eji.1830230435

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Toxoplasma gondii tachyzoites invaded and replicated in cultured rat small intestine cells of the line IEC-6. Treatment of rat small intestine cells with murine recombinant interferon-gamma resulted in a dose-dependent inhibition of intracellular T gondii replication. This could be of relevance as a first line defense against Toxoplasma infection.

引用

页码：981 / 983

页数：3

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