Behavioral effects of felbamate in childhood epileptic encephalopathy (Lennox-Gastaut syndrome)

被引:16
作者
Gay, PE [1 ]
Mecham, GF [1 ]
Coskey, JS [1 ]
Sadler, T [1 ]
Thompson, JA [1 ]
机构
[1] UNIV UTAH,SCH MED,WESTMINSTER COLL,PRIMARY CHILDRENS HOSP,SALT LAKE CITY,UT 84112
关键词
D O I
10.2466/pr0.1995.77.3f.1208
中图分类号
B84 [心理学];
学科分类号
04 ; 0402 ;
摘要
The behavioral effects of felbamate were assessed in 20 persons (ages 2 to 19 years) who were participating in a compassionate plea protocol for children with Lennox-Gastaut syndrome. Parents completed a questionnaire concerning aspects of behavioral change once all medications were in a constant regimen. Significant improvements were suggested in social functioning, intellectual functioning, motor functioning, attention and concentration, alertness, initiative, variability in performance, and memory. There was a tendency for these effects to reverse when the drug was discontinued.
引用
收藏
页码:1208 / 1210
页数:3
相关论文
共 3 条
[1]  
LEPPIK IE, 1989, ANTIEPILEPTIC DRUGS, P983
[2]  
NEIDERMEYER E, 1988, LENNOXGASTAUT SYNDRO
[3]  
1993, NEW ENGL J MED, V328, P29