ANALYSIS OF MODE OF ACTION OF HERBICIDAL ALPHA-CHLOROACETAMIDES

Selectivity of α-chloroacetamides is based on differential rates of metabolism or detoxification between sensitive and resistant plant species. However, physiological effects cannot be explained. Investigations have now focused attention upon protein synthesis as the general locus of interaction, although the reactivity of the α-chloroacetamides with nucleophiles suggests the possibility of multiple sites of action. © 1969, American Chemical Society. All rights reserved.