FLUORESCENCE CHANGES DURING CONDUCTION IN NERVES STAINED WITH ACRIDINE ORANGE

被引：42

作者：

TASAKI, I

CARNAY, L

SANDLIN, R

WATANABE, A

机构：

[1] Laboratory of Neurobiology, National Institute of Mental Health, Bethesda

[2] Tokyo Medical and Dental University, Tokyo

来源：

SCIENCE | 1969年 / 163卷 / 3868期

关键词：

D O I：

10.1126/science.163.3868.683

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Nerves from spider crabs and squid fluoresce when stained with Acridine Orange. The intensity of fluorescence increases during nerve conduction. Prolongation of the electric response in the squid axon is associated with a fluorescence change of similar duration. These findings suggest that the physicochemical properties of the macromolecules around the dye molecules in the nerve membrane drastically change during the process of nerve conduction.

引用

页码：683 / &

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