ALPHA-KETOGLUTARATE AND POSTOPERATIVE MUSCLE CATABOLISM

被引:98
作者
WERNERMAN, J
HAMMARQVIST, F
VINNARS, E
机构
[1] KAROLINSKA INST,ST GORANS CHILDRENS HOSP,DEPT SURG,S-11281 STOCKHOLM,SWEDEN
[2] KAROLINSKA INST,ST GORANS CHILDRENS HOSP,METAB RES LAB,S-11281 STOCKHOLM,SWEDEN
关键词
D O I
10.1016/0140-6736(90)90811-I
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The hypothesis that muscle protein catabolism after trauma is associated with a shortage of α-ketoglutarate, rather than glutamine, was tested. Addition of α-ketoglutarate to postoperative total parenteral nutrition prevented the decrease in muscle protein synthesis and free glutamine that usually occurs after surgery. α-ketoglutarate supplementation may improve recovery after trauma. © 1990.
引用
收藏
页码:701 / 703
页数:3
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