THE DENTATE GYRUS IS SEXUALLY DIMORPHIC IN PREPUBESCENT RATS - TESTOSTERONE PLAYS A SIGNIFICANT ROLE

被引：81

作者：

ROOF, RL ^{[1
]}

机构：

[1] UNIV NEVADA,DEPT PSYCHOL,RENO,NV 89557

来源：

BRAIN RESEARCH | 1993年 / 610卷 / 01期

关键词：

HIPPOCAMPUS; SPATIAL MEMORY; STEROID HORMONE;

D O I：

10.1016/0006-8993(93)91228-K

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

In a morphological examination of the hippocampal formation of pre-pubescent rats, a testosterone-related sexual dimorphism was observed. The dentate gyrus granule cell layer was greater (8-9%) in width and length and laterally asymmetrical in males and in testosterone-treated females. This dimorphism was previously observed in adult rats. These data demonstrate that the dimorphism exists prior to puberty and is therefore not dependent on hormone changes associated with this event. In addition, a correlation between the size of this cell layer and performance on a spatial task were observed.

引用

页码：148 / 151

页数：4

共 18 条

[1] BEST PJ, 1989, PSYCHOBIOLOGY, V17, P236
[2] ACQUISITION OF A COMPLEX PLACE TASK IN RATS WITH SELECTIVE IBOTENATE LESIONS OF HIPPOCAMPAL-FORMATION - COMBINED LESIONS OF SUBICULUM AND ENTORHINAL CORTEX VERSUS HIPPOCAMPUS
BOUFFARD, JP
JARRARD, LE
[J]. BEHAVIORAL NEUROSCIENCE, 1988, 102 (06) : 828 - 834
[3] SYMMETRICAL MAZE - AN AUTOMATED CLOSED-FIELD TEST SERIES FOR RATS
DAVENPOR.JW
HAGQUIST, WW
RANKIN, GR
[J]. BEHAVIOR RESEARCH METHODS & INSTRUMENTATION, 1970, 2 (03): : 112 - &
[4] SEX-DIFFERENCES IN SPATIAL ABILITY - AN EVOLUTIONARY HYPOTHESIS AND TEST
GAULIN, SJC
FITZGERALD, RW
[J]. AMERICAN NATURALIST, 1986, 127 (01) : 74 - 88
[5] GOULD E, 1990, J NEUROSCI, V10, P1286
[6] HALPERN DF, 1986, SEX DIFFERENCES COGN, P48
[7] GONADAL-STEROIDS AND BRAIN-DEVELOPMENT
MCEWEN, BS
[J]. BIOLOGY OF REPRODUCTION, 1980, 22 (01) : 43 - 48
[8] INTERACTION OF AGE AND SEX IN SYMPATHETIC AXON INGROWTH INTO THE HIPPOCAMPUS FOLLOWING SEPTAL AFFERENT DAMAGE
MILNER, TA
LOY, R
[J]. ANATOMY AND EMBRYOLOGY, 1980, 161 (02): : 159 - 168
[9] HIPPOCAMPUS - COGNITIVE MAP OR WORKING MEMORY
NADEL, L
MACDONALD, L
[J]. BEHAVIORAL AND NEURAL BIOLOGY, 1980, 29 (03): : 405 - 409
[10] HIPPOCAMPUS AS A SPATIAL MAP - PRELIMINARY EVIDENCE FROM UNIT ACTIVITY IN FREELY-MOVING RAT
OKEEFE, J
DOSTROVS.J
[J]. BRAIN RESEARCH, 1971, 34 (01) : 171 - &

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