COMPARISON BETWEEN THE ALLELIC FREQUENCY-DISTRIBUTION OF THE HA-RAS1 LOCUS IN NORMAL INDIVIDUALS AND PATIENTS WITH LYMPHOMA, BREAST, AND OVARIAN-CANCER

被引：30

作者：

CORELL, B

ZOLL, B

机构：

来源：

HUMAN GENETICS | 1988年 / 79卷 / 03期

关键词：

D O I：

10.1007/BF00366247

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Analysis of 426 alleles of the human Ha-ras1 locus in DNA samples of cancer patients and controls reveals no obvious association between specific restriction fragments and a genetic predisposition to malignancy. However, differences in the allele distribution in leukocyte and tumour DNAs of cancer patients may be related to an involvement of the Ha-ras1 gene in tumorigenesis.

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页码：255 / 259

页数：5

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