MIXED LEUKOCYTE REACTION AS A POSSIBLE TEST OF ZYGOSITY IN TWINS

被引：5

作者：

JARVIK, LF

FALEK, A

SCHMIDT, R

PLATT, M

机构：

[1] Department of Medical Genetics, New York State Psychiatric Institute, College of Physicians and Surgeons, Columbia University, New York, NY

来源：

HUMAN HEREDITY | 1969年 / 19卷 / 06期

关键词：

D O I：

10.1159/000152282

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The usefulness of the mixed leukocyte reaction (MLR) as a possible method of zygosity diagnosis was investigated and a significantly stronger MLR was demonstrated in cultures composed of mixed cells from dizygotic cotwins or unrelated persons than in cultures containing cells from monozygotic twin partners. Although, unlike reciprocal skin grafts, the MLR is not a definitive test for zygosity, it should prove a valuable additional tool for the exclusion of monozygosity, particularly when used in conjunction with dermatoglvphics and blood group determinations. © 1969 S. Karger AG, Basel.

引用

页码：668 / &

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