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ANTHELMINTIC EFFECTS OF FLUBENDAZOLE ON BRUGIA-PAHANGI

被引：56
作者：
DENHAM, DA
SAMAD, R
CHO, SY
SUSWILLO, RR
SKIPPINS, SC
机构：
[1] Department of Medical Helminthalogy, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, Keppel Street
[2] Department of Parasitology, College of Medicine, Seoul National University, Seoul
来源：
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE | 1979年 / 73卷 / 06期
基金：
英国医学研究理事会;
关键词：
D O I：
10.1016/0035-9203(79)90018-X
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
The anthelmintic effects of flubendazole (methyl [5-(4-fluorobenzoyl)-1 -H-benzimidazol-2-yl] carbamate) (Janssen Pharmaceutics) were evaluated in jirds (Meriones unguiculatus) and cats (Felis cattus) infected with Brugia pahangi. Flubendazole was macrofilaricidal at 5×2·5 mg/kg and 1×25 mg/kg in jirds and 1×100 mg/kg in cats when administered by subcutaneous injection. It also killed developing larvae in jirds. It was not microfilaricidal. © 1979 Oxford University Press.
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页码：673 / 676
页数：4
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