CROSS-LINKING OF ACTIN-FILAMENTS BY HEAVY-MEROMYOSIN

被引:51
作者
TRINICK, J [1 ]
OFFER, G [1 ]
机构
[1] UNIV LONDON KINGS COLL,DEPT BIOPHYS,LONDON WC2B 5RL,ENGLAND
基金
英国医学研究理事会;
关键词
D O I
10.1016/0022-2836(79)90407-8
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The structure of acto-heavy meromyosin has been examined by electron microscopy. When heavy meromyosin is mixed with actin at ~ 2 mg/ml a gel is formed. At lower actin concentrations more ordered assemblies are formed in which the actin filaments are in rafts" about 300 Å apart cross-linked by heavy meromyosin. These results indicate that in solution the two heads of a heavy meromyosin molecule can bind to different actin filaments. © 1979."
引用
收藏
页码:549 / 556
页数:8
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