CROSS-LINKING OF ACTIN-FILAMENTS BY HEAVY-MEROMYOSIN

被引：51

作者：

TRINICK, J ^{[1
]}

OFFER, G ^{[1
]}

机构：

[1] UNIV LONDON KINGS COLL,DEPT BIOPHYS,LONDON WC2B 5RL,ENGLAND

来源：

JOURNAL OF MOLECULAR BIOLOGY | 1979年 / 133卷 / 04期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/0022-2836(79)90407-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The structure of acto-heavy meromyosin has been examined by electron microscopy. When heavy meromyosin is mixed with actin at ~ 2 mg/ml a gel is formed. At lower actin concentrations more ordered assemblies are formed in which the actin filaments are in rafts" about 300 Å apart cross-linked by heavy meromyosin. These results indicate that in solution the two heads of a heavy meromyosin molecule can bind to different actin filaments. © 1979."

引用

页码：549 / 556

页数：8

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