SAMPLE-SIZE ESTIMATION FOR COMPARING 2 OR MORE TREATMENT GROUPS IN CLINICAL-TRIALS

被引：47

作者：

DAY, SJ

GRAHAM, DF

机构：

[1] Lilly Research Centre Limited, Windlesham, Surrey, GU20 6PH, Erl Wood Manor

[2] Maidenhead, Berkshire, SL6 6SB, 26 Cranbrook Drive, Pinkneys Green

来源：

STATISTICS IN MEDICINE | 1991年 / 10卷 / 01期

关键词：

D O I：

10.1002/sim.4780100109

中图分类号：

Q [生物科学];

学科分类号：

07 [理学]; 0710 [生物学]; 09 [农学];

摘要：

Methods for estimating required sample size for comparing two population means have been published. Most involve the use of complicated formulae and tables. These methods are limited to comparing two groups. Although techniques exist to determine sample sizes for comparing more than two groups, they are intrinsically far more complicated. A simple linear nomogram is proposed as a solution to these problems, and its use is illustrated with examples of parallel group, ordered parallel group and factorial designs.

引用

页码：33 / 43

页数：11

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