SCHIZOPHRENIA FOLLOWING PRENATAL EXPOSURE TO INFLUENZA EPIDEMICS BETWEEN 1939 AND 1960

被引：216

作者：

SHAM, PC

OCALLAGHAN, E

TAKEI, N

MURRAY, GK

HARE, EH

MURRAY, RM

机构：

[1] KINGS COLL HOSP,DEPT PSYCHOL MED,DE CRESPIGNY PK,LONDON SE5 8AF,ENGLAND

[2] CLUAIN MHUIRE FAMILY CTR,BLACKROCK,IRELAND

[3] BETHLEM ROYAL & MAUDSLEY HOSP,LONDON,ENGLAND

[4] INST PSYCHIAT,GENET SECT,LONDON SE5 8AF,ENGLAND

[5] MAUDSLEY HOSP & INST PSYCHIAT,LONDON SE5 8AZ,ENGLAND

来源：

BRITISH JOURNAL OF PSYCHIATRY | 1992年 / 160卷

基金：

英国惠康基金;

关键词：

D O I：

10.1192/bjp.160.4.461

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

We examined the relationship between the dates of births of schizophrenic patients admitted to hospitals for the first time in England and Wales between 1970 and 1979, and the occurrence of influenza epidemics between 1939 and 1960. Our results indicate that exposure to influenza epidemics between the third and seventh month of gestation is associated with schizophrenia in adult life. The hypothesis that maternal viral infection is an important cause of schizophrenia can explain many aspects of the enigmatic epidemiology of the condition.

引用

页码：461 / 466

页数：6

共 29 条

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[2]

BOWLER AE, 1990, ARCH GEN PSYCHIAT, V47, P876

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