LITHIUM TRANSPORT ACROSS RED-CELL MEMBRANE - CELL-MEMBRANE ABNORMALITY IN MANIC-DEPRESSIVE ILLNESS

被引：63

作者：

DORUS, E

PANDEY, GN

SHAUGHNESSY, R

GAVIRIA, M

VAL, E

ERICKSEN, S

DAVIS, JM

机构：

[1] ILLINOIS STATE PSYCHIAT INST, DEPT RES, CHICAGO, IL 60612 USA

[2] UNIV ILLINOIS, SCH MED, DEPT PSYCHIAT, CHICAGO, IL 60612 USA

[3] UNIV CALIF DAVIS, SACRAMENTO MED CTR, DEPT PSYCHIAT, SACRAMENTO, CA 95817 USA

来源：

SCIENCE | 1979年 / 205卷 / 4409期

关键词：

D O I：

10.1126/science.472716

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

In the families of manic-depressive patients, relatives with a history of affective disorders had a significantly higher ratio of mean red cell lithium to plasma lithium in vitro than relatives with no such history. A genetically controlled abnormality in lithium-sodium transport, the mechanism that determines the lithium ratio, may play a role in the etiology of some forms of affective disorders. Copyright © 1979 AAAS.

引用

页码：932 / 934

页数：3

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