A LIGAND STRUCTURE-ENANTIOSELECTIVITY RELATIONSHIP FOR THE OSMIUM-CATALYZED ASYMMETRIC DIHYDROXYLATION OF OLEFINS

被引：43

作者：

OGINO, Y ^{[1
]}

CHEN, H ^{[1
]}

MANOURY, E ^{[1
]}

SHIBATA, T ^{[1
]}

BELLER, M ^{[1
]}

LUBBEN, D ^{[1
]}

SHARPLESS, KB ^{[1
]}

机构：

[1] MIT,DEPT CHEM,CAMBRIDGE,MA 02139

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 41期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0040-4039(00)93549-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The highest enantioselectivities to date for various olefins are obtained in the osmiumcatalyzed asymmetric dihydroxylation using new 9-O-aromatic dihydroquinidine and dihydroquinine ligands. A ligand structure-enantioselectivity relationship (LSER) is developed, and representative results for quinine-based ligands are reported for the first time.

引用

页码：5761 / 5764

页数：4

共 13 条

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