IN-111 LABELED MN-METALLOPORPHYRIN FOR TUMOR IMAGING

被引：17

作者：

NAKAJIMA, S

YAMAUCHI, H

SAKATA, I

HAYASHI, H

YAMAZAKI, K

MAEDA, T

KUBO, Y

SAMEJIMA, N

TAKEMURA, T

机构：

[1] NIHONMEDIPHYS CO LTD,CHIBA 29902,JAPAN

[2] TOYOHAKKA CO LTD,OKAYAMA 71003,JAPAN

[3] HOKKAIDO UNIV,INST APPL ELECT,DEPT CHEM,SAPPORO,HOKKAIDO 060,JAPAN

[4] ASAHIKAWA MED COLL,DEPT SURG 1,ASAHIKAWA 078,JAPAN

来源：

NUCLEAR MEDICINE AND BIOLOGY | 1993年 / 20卷 / 02期

关键词：

D O I：

10.1016/0969-8051(93)90120-J

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

We synthesized and developed a new tumor imaging agent, In-111-labeled metalloporphyrin (In-111-ATN-10) which consists of a carrier (ATN-10) of the tumor imaging possessing both a non-radioactive manganese complex in the porphyrin ring and a bifunctional chelating group (DTPA) attached to its side chain. The images of the three kinds of tumors were delineated more clearly by In-111-ATN-10 than Ga-67-citrate. Moreover, there was no photosensitivity in ATN-10. In-111-ATN-10 is studied as a new tumor positive scintigraphic agent instead of Ga-67-citrate.

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收藏

页码：231 / 237

页数：7

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