ANTICIPATORY IMMUNE CHANGES IN WOMEN TREATED WITH CHEMOTHERAPY FOR OVARIAN-CANCER

被引：14

作者：

LEKANDER, M

FURST, CJ

ROTSTEIN, S

BLOMGREN, H

FREDRIKSON, M

机构：

[1] KAROLINSKA INST,DEPT CLIN NEUROSCI,STOCKHOLM,SWEDEN

[2] KAROLINSKA HOSP,DEPT ONCOL,RADIUMHEMMET,S-17176 STOCKHOLM,SWEDEN

[3] DANDERYD HOSP,DEPT GEN ONCOL,S-18288 DANDERYD,SWEDEN

[4] UPPSALA UNIV,DEPT CLIN PSYCHOL,UPPSALA,SWEDEN

来源：

INTERNATIONAL JOURNAL OF BEHAVIORAL MEDICINE | 1995年 / 2卷 / 01期

关键词：

IMMUNE SYSTEM; PSYCHONEUROIMMUNOLOGY; CONDITIONING; STATE ANXIETY; NAUSEA; CHEMOTHERAPY;

D O I：

10.1207/s15327558ijbm0201_1

中图分类号：

B849 [应用心理学];

学科分类号：

040203 ;

摘要：

Immune parameters were assessed in 22 women before chemotherapy for ovarian cancer and compared with assessment made at home 2 days earlier. In the hospital, as compared to home measures, patients had a lower percentage of lymphocytes and monocytes and a higher percentage of granulocytes. Absolute numbers of lymphocytes were lower at the hospital as compared to at home. T-cell proliferative responses to concanavalin A were elevated for cells isolated from hospital blood samples as compared to home samples. The observed changes in immune parameters were not related to levels of state anxiety at home or at the hospital. The results show anticipatory immune changes in a group of patients receiving chemotherapy that did not include cyclophosphamide.

引用

页码：1 / 12

页数：12

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