COMPLEMENTATION OF BETA-GALACTOSIDASE IN FUSED CELLS OF MUCOLIPIDOSIS-II WITH ANOTHER VARIANTS OF BETA-GALACTOSIDASE DEFICIENCY USING NEW SINGLE CELL ENZYME ASSAY

被引：10

作者：

OKADA, S ^{[1
]}

KATO, T ^{[1
]}

YABUUCHI, H ^{[1
]}

OKADA, Y ^{[1
]}

机构：

[1] OSAKA UNIV, MICROBIAL DIS RES INST, SUITA, OSAKA 565, JAPAN

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1979年 / 88卷 / 02期

关键词：

D O I：

10.1016/0006-291X(79)92084-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

By cell fusion and new single cell hydroalse assay technique, the complementation was observed between mucolipidosis II and other two hereditary lysosomal β-galactosidase deficient disorders, GM1-gangliosidosis, type 2 and β-galactosidase deficient-type mucolipidosis. The possible mechanisms with which abnormal ML-II β-galactosidase was modified and normalized by other two different cell strains were discussed. © 1979.

引用

页码：559 / 562

页数：4

共 11 条

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[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1977, 74 (05) : 2026 - 2030
[4] PHOSPHOHEXOSYL RECOGNITION IS A GENERAL CHARACTERISTIC OF PINOCYTOSIS OF LYSOSOMAL GLYCOSIDASES BY HUMAN FIBROBLASTS
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[J]. CLINICA CHIMICA ACTA, 1978, 86 (02) : 159 - 167
[9] OKADA S, UNPUBLISHED
[10] EVIDENCE FOR LYSOSOMAL ENZYME RECOGNITION BY HUMAN FIBROBLASTS VIA A PHOSPHORYLATED CARBOHYDRATE MOIETY
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