AMINO-SUBSTITUTED BETA-BENZYL-C-GLYCOSIDES - NOVEL BETA-GLYCOSIDASE INHIBITORS

被引：70

作者：

SCHMIDT, RR

DIETRICH, H

机构：

[1] Fakultät Für Chemie, Universität Konstanz, W-7760

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1991年 / 30卷 / 10期

关键词：

D O I：

10.1002/anie.199113281

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Deoxy and amino substituted benzyl-C-glucosides were prepared and their properties as beta-glucosidase inhibitors were studied. Compound 1 proved to be an efficient competitive inhibitor (K(i) = 7.0 x 10(-5) M), with an activity comparable with that of deoxynojirimycin.

引用

页码：1328 / 1329

页数：2

共 19 条

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