OXIDATION OF CHOLESTEROL BY HYDROXYL RADICAL

被引：29

作者：

ANSARI, GAS

SMITH, LL

机构：

[1] Division of Biochemistry, Department of Human Biological Chemistry and Genetics, University of Texas Medical Branch, Galveston, Texas

来源：

PHOTOCHEMISTRY AND PHOTOBIOLOGY | 1979年 / 30卷 / 01期

关键词：

D O I：

10.1111/j.1751-1097.1979.tb07127.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Abstract— The oxidation of chblesterol by hydroxyl radical generated by 60Co y‐radiolysis of aqueous cholesterol dispersions or of dispersions saturated with N2O ave in low yields the products 38‐hydroxy‐cholest‐5‐en‐7‐one. the epimeric cholest‐5‐ene‐3β,7‐diols, 5,6α‐epoxy‐5α‐cholestan‐3β‐ol, 5.6β‐epoxy‐5β‐cholestan‐3,β‐ol, and 5α‐cholestane‐38,5,6β‐triol. Sterol hydroperoxides were not detected except in the radiolysis of dispersions saturated with oxygen. Copyright © 1979, Wiley Blackwell. All rights reserved

引用

页码：147 / 150

页数：4

共 19 条

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