DEATH FROM INSIDE-OUT - AN OVERVIEW

被引:62
作者
WYLLIE, AH
机构
[1] Department of Pathology, University Medical School, Edinburgh
关键词
D O I
10.1098/rstb.1994.0099
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Although a type of cell death strategically suited to participating in developmental processes has been well known for nearly thirty years, it is only in the recent past that the extraordinary ubiquity of such death has been appreciated. Apoptosis, a term first employed to describe such death defined in structural terms, is associated with a stereotyped set of effector processes, and is driven by genes most of which are familiar as oncogenes or oncosuppressor genes. Dysregulation of apoptosis leads to diseases of enormous social importance such as cancer and AIDS.
引用
收藏
页码:237 / 241
页数:5
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