REGIONAL LOCALIZATION OF HUMAN-CHROMOSOME-15 LOCI

被引：15

作者：

RICHARD, I

BROUX, O

CHIANNILKULCHAI, N

FOUGEROUSSE, F

ALLAMAND, V

BOURG, N

BRENGUIER, L

DEVAUD, C

PASTURAUD, P

ROUDAUT, C

LORENZO, F

SEBASTIANIKABATCHIS, C

SCHULTZ, RA

POLYMEROPOULOS, MH

GYAPAY, G

AUFFRAY, C

BECKMANN, JS

机构：

[1] CTR ETUD POLYMORPHISME HUMAIN,FDN JEAN DAUSSET,F-75010 PARIS,FRANCE

[2] GENETHON,DEPT LOCALIZAT,F-91000 EVRY,FRANCE

[3] GENETHON,GENEXPRESS PROGRAM,F-91000 EVRY,FRANCE

[4] GENETHON,DEPT GENET MAPPING,F-91000 EVRY,FRANCE

[5] UNIV TEXAS,SW MED CTR DALLAS,DALLAS,TX 75235

[6] NIH,NATL CTR HUMAN GENOME RES,BETHESDA,MD 20892

[7] CNRS,UPR 420,F-94801 VILLEJUIF,FRANCE

来源：

GENOMICS | 1994年 / 23卷 / 03期

关键词：

D O I：

10.1006/geno.1994.1550

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

One hundred forty-nine chromosome 15 loci were mapped by PCR with respect to chromosome breakpoints in three somatic cell hybrids retaining total or part of chromosome 15 and to a 10-Mb YAC contig. This chromosome was subdivided into 5 regions, yielding an average resolution of more than 1 sequence tagged site per megabase. The mapped loci included 18 genes, 60 cDNA-derived sequence tagged sites, and 69 microsatellites. In addition, the amount of chromosome 15 retained in line A15.1 has been defined. This work represents the first attempt at an integration of the human physical, expression, and genetic maps of chromosome 15. (C) 1994 Academic Press, Inc.

引用

页码：619 / 627

页数：9

共 45 条

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