SEQUENCE OF THE SUPEROXIDE-DISMUTASE 1 (SOD 1) GENE IN FAMILIAL PARKINSONS-DISEASE

被引：24

作者：

BANDMANN, O ^{[1
]}

DAVIS, MB ^{[1
]}

MARSDEN, CD ^{[1
]}

HARDING, AE ^{[1
]}

机构：

[1] UNIV LONDON,INST NEUROL,DEPT CLIN NEUROL,NEUROGENET SECT,LONDON WC1N 3BG,ENGLAND

来源：

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY | 1995年 / 59卷 / 01期

关键词：

PARKINSONS DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; SUPEROXIDE DISMUTASE;

D O I：

10.1136/jnnp.59.1.90

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Mutations in the superoxide dismutase 1 (SOD1) gene have been detected in affected members of some families with familial amyotrophic lateral sclerosis. To evaluate the possibility of a shared genetic defect in amyotrophic lateral sclerosis and Parkinson's disease, the SOD1 gene was sequenced in index patients with familial Parkinson's disease from 23 families. No changes were detected.

引用

页码：90 / 91

页数：2

共 20 条

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