PORCINE LACTIC DEHYDROGENASE IN SERUM OF PATIENTS TREATED BY EXTRACORPOREAL PORCINE LIVER PERFUSION

被引：5

作者：

BERSOHN, I

KEW, MC

ROLLE, M

MIENY, CJ

MYBURGH, JA

机构：

[1] Clinical Pathology and Head of the Liver Function and Enzyme Units, South African Institute for Medical Research, Johannesburg

[2] Department of Medicine, University of the Witwatersrand, Johannesburg

[3] South African Institute for Medical Research, Johannesburg

[4] Department of Surgery, University of the Witwatzrsrand, Johannesburg

来源：

BRITISH MEDICAL JOURNAL | 1969年 / 2卷 / 5649期

关键词：

D O I：

10.1136/bmj.2.5649.84

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Porcine lactic dehydrogenase (L.D.H.) has been found in the serum of four patients in hepatic coma treated by extracorporeal porcine liver perfusion. A comparison between the porcine L.D.H. isoenzyme pattern in the patients' serum and that in porcine serum and liver extract indicates that the porcine L.D.H. is derived from the pig liver. This finding reflects damage to the pig liver cells sustained during porcine hepatectomy and subse- quent perfusion. Possibly patients might develop immune reactions against porcine substances when these entered the circulation, especially if perfusion was repeated after an interval of some time. © 1969, British Medical Journal Publishing Group. All rights reserved.

引用

页码：84 / &

共 8 条

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