AMINO-ACIDS AND PEPTIDES .73. WHAT ARE THE STRUCTURES OF FENESTIN-A AND FENESTIN-B

被引：10

作者：

SCHMIDT, U ^{[1
]}

LIEBERKNECHT, A ^{[1
]}

KAZMAIER, U ^{[1
]}

HASLINGER, E ^{[1
]}

机构：

[1] UNIV BAYREUTH,INST ORGAN CHEM,W-8580 BAYREUTH,GERMANY

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1990年 / 29卷 / 05期

关键词：

D O I：

10.1002/anie.199005141

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

1H NMR signals at unusually high field (δ = 3.9–4.1 rather than 4.0–4.6 as in known cyclopeptides) render the proposed structures 1 and 2 unlikely for fenestin A and fenestin B, two cyclopeptides isolated from Pacific sponges. Synthesis and analysis of the postulated compound 2 as well as the dimer of 1 have made it possible to show that the suggested structure for fenestin B is wrong, while that for fenestin A must at least be regarded as questionable. (Formula Presented.) Copyright © 1990 by VCH Verlagsgesellschaft mbH, Germany

引用

收藏

页码：514 / 515

页数：2

相关论文

共 15 条

[1] ISOLATION AND STRUCTURAL ELUCIDATION OF CHLAMYDOCIN [J].

CLOSSE, A ;

HUGUENIN, R .

HELVETICA CHIMICA ACTA, 1974, 57 (03) :533-545

[2] STRUCTURE OF CYL-2, A NOVEL CYCLOTETRAPEPTIDE FROM CYLINDROCLADIUM-SCOPARIUM [J].

HIROTA, A ;

SUZUKI, A ;

AIZAWA, K ;

TAMURA, S .

AGRICULTURAL AND BIOLOGICAL CHEMISTRY, 1973, 37 (04) :955-956

[3] THE STRUCTURE AND CONFORMATION OF HC-TOXIN [J].

KAWAI, M ;

RICH, DH ;

WALTON, JD .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1983, 111 (02) :398-403

[4] NONSELECTIVE PHYTOTOXINS SIMULTANEOUSLY PRODUCED WITH HOST-SELECTIVE ACTG-TOXINS BY A PATHOTYPE OF ALTERNARIA-CITRI CAUSING BROWN SPOT DISEASE OF MANDARINS [J].

KONO, Y ;

GARDNER, JM ;

TAKEUCHI, S .

AGRICULTURAL AND BIOLOGICAL CHEMISTRY, 1986, 50 (09) :2401-2403

[5] NOVEL MARINE SPONGE DERIVED AMINO-ACIDS .7. THE FENESTINS [J].

OMAR, S ;

TENENBAUM, L ;

MANES, LV ;

CREWS, P .

TETRAHEDRON LETTERS, 1988, 29 (43) :5489-5492

[6]

RICH DH, 1974, TETRAHEDRON LETT, P4037

[7] THE REVISED STRUCTURE OF BOTTROMYCIN-A2 [J].

SCHIPPER, D .

JOURNAL OF ANTIBIOTICS, 1983, 36 (08) :1076-1077

[8] SYNTHESIS OF PEPTIDE ALKALOIDS .5. NEW METHOD FOR SYNTHESIS OF ANSA PEPTIDES - AMINO-ACIDS AND PEPTIDES .34. [J].

SCHMIDT, U ;

LIEBERKNECHT, A ;

GRIESSER, H ;

TALBIERSKY, J .

JOURNAL OF ORGANIC CHEMISTRY, 1982, 47 (17) :3261-3264

[9]

TAKAYAMA S, 1982, AGR BIOL, P3261

[10]

TEMPLETON GE, 1972, MICROB TOXINS, V8, P160