PREPARATION OF A WELL-DEFINED SUGAR-PEPTIDE CONJUGATE - A POSSIBLE APPROACH TO A SYNTHETIC VACCINE AGAINST NEISSERIA-MENINGITIDIS

被引：17

作者：

BOONS, GJPH ^{[1
]}

HOOGERHOUT, P ^{[1
]}

POOLMAN, JT ^{[1
]}

VANDERMAREL, GA ^{[1
]}

VANBOOM, JH ^{[1
]}

机构：

[1] RIJKSINST VOLKSGEZONDHEID & MILIEU HYG,BACTERIAL VACCINE DEV UNIT,3720 BA BILTHOVEN,NETHERLANDS

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1991年 / 1卷 / 06期

关键词：

D O I：

10.1016/S0960-894X(01)80813-1

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A phosphorylated disaccharide from the inner core region of Neisseria meningitidis immunotype lipopolysaccharide 6 could be conjugated via an artificial spacer to an elongated peptide sequence of a meningococcal outer membrane protein.

引用

页码：303 / 308

页数：6

共 29 条

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