FOSFOMYCIN TROMETAMOL VERSUS PIPEMIDIC ACID IN THE TREATMENT OF BACTERIURIA IN PREGNANCY

被引：20

作者：

ZINNER, S

机构：

来源：

CHEMOTHERAPY | 1990年 / 36卷

关键词：

BACTERIURIA; PREGNANCY; FOSFOMYCIN; PIPEMIDIC ACID; URINARY INFECTION;

D O I：

10.1159/000238818

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The Italian multihospital study of bacteriuria in pregnancy randomized 153 pregnant bacteriuric patients to receive fosfomycin trometamol (FT) as a single dose of 3 g and 138 such patients to receive conventional therapy with pipemidic acid (PA), 400 mg b.i.d. for 7 days. The two groups were well matched for age, parity, pregnancy course, symptoms and past history of cystitis. Infecting organisms were eradicated in 147 (96%) of FT and 129 (94%) of PA patients. Similar recurrence rates occurred. Minimal side effects (mostly nausea and dyspepsia) occurred (9% FT; 15% PA). Single-dose FT appeared equivalent to conventional treatment with PA.

引用

页码：50 / 52

页数：3