BIOPHARMACOLOGICAL DATA AND HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC ANALYSIS OF 1,4-BENZODIAZEPINES IN BIOLOGICAL-FLUIDS - A REVIEW

被引：47

作者：

BERRUETA, LA

GALLO, B

VICENTE, F

机构：

[1] Departamento de Química Analítica, Facultad de Ciencias, Universidad del País Vasco, 48080 Bilbao, Apdo

来源：

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | 1992年 / 10卷 / 2-3期

关键词：

1,4-BENZODIAZEPINES; BIOPHARMACOLOGICAL DATA; HPLC; ANALYSIS IN BIOLOGICAL FLUIDS;

D O I：

10.1016/0731-7085(92)80019-J

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A review with 123 references on the analysis of 1,4-benzodiazepines in biological samples using HPLC is presented. Some important physico-chemical and biopharmacological data for the development of analytical methods are collected. Different methods of sample pretreatment, chromatographic conditions and detection systems are discussed.

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页码：109 / 136

页数：28

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